Mechanisms of Multidrug Transport Proteins

Mechanisms of Multidrug Transport Proteins

Caption

Fig. 1: Snapshot from MD simulation of transporter associated with antigen processing (TAP) embedded in a lipid anodisc. TAP is shown in cyan and orange, whereas the nanodisc proteins and lipids are colored yellow and grey, respectively. The red molecule at the right is the ICP47 protein from herpes simplex virus, a high-affinity inhibitor of TAP. The transmission microgram in the background shows the preparation of herpes simplex virus.

Participating Universities